During the 13th-15th centuries, the Church of Valencia maintained a constant evangelizing activity, aiming at the conversion of both Muslims and Jews, as well as the development of the Christians’ faith who settled in these generous lands.

Of great significance for Christianity was the end of the Western Schism, which took place after the death of Benedict XIII (the Aragonese Pedro de Luna) in Peñíscola (Castellon) in 1423 and the resignation of his successor Clement VIII (Gil Sánchez Muñoz, native of Teruel and canon of the Cathedral of Valencia) in the town of Saint Matthew (Castellón) in 1429.

During the transition from the 14th to the 15th century, a turbulent period with epidemics and wars, the evangelizing and peace mission of the Dominican Saint Vincent Ferrer (Valencia 1350 – Vannes, Vannes, Brittany, 1419) shone in Valencia, Spain and Western Europe.

In 1410 the Saint created in Valencia the current Imperial College of orphaned children that bears his name.